Académico · Postgrado UdeC
JORGE PATRICIO FUENTEALBA ARCOS
Doctor en Medicina y Cirugía
Universidad Autónoma de Madrid
jorgefuentealba@udec.cl-
Molecular Mechanism of Beta-Amyloid Aggregation Inhibition by KLVFF
JOURNAL OF CHEMICAL INFORMATION AND MODELING 2026 ARTÍCULO WOS - SCOPUS AUTOR
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Unraveling the neuroprotective mechanisms of elephant black garlic extract against beta amyloid peptide-induced neurotoxicity
FRONTIERS IN NUTRITION 2026 ARTÍCULO WOS - SCOPUS AUTOR
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Deciphering the Neurotoxic Effects of Karenia selliformis
TOXINS 2025 ARTÍCULO WOS - SCOPUS AUTOR
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Allosteric modulation and direct activation of glycine receptors by a tricyclic sulfonamide.
SCIENTIFIC REPORTS 2025 ARTÍCULO WOS - SCOPUS AUTOR
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The Alkaloid Gelsemine Reduces Aß Peptide Toxicity by Targeting Transglutaminase Type 2 Enzyme
PLANTS-BASEL 2025 ARTÍCULO WOS - SCOPUS AUTOR
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Neuronal ion channel modulation by Drimys winteri compounds: Opening a new chemical space to neuropharmacology
NEURAL REGENERATION RESEARCH 2025 REVIEW WOS - SCOPUS AUTOR
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Potential Antioxidant and Neuroprotective Effect of Polysaccharide Isolated from Digüeñe Cyttaria espinosae
JOURNAL OF FUNGI 2025 ARTÍCULO WOS - SCOPUS AUTOR
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Neuroprotective Activity of 3-((6-(Phenylethynyl)pyridin-3- yl)oxy)quinuclidine: A Potential Ligand for the Treatment of Alzheimer's Disease
ACS CHEMICAL NEUROSCIENCE 2025 ARTÍCULO WOS - SCOPUS AUTOR
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In Silico Characterization of Gelsemium Compounds as Glycine Receptor Ligands
COMPOUNDS 2025 ARTÍCULO EMERGENTE - SCOPUS AUTOR
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Molecular Pharmacology of Gelsemium Alkaloids on Inhibitory Receptors
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2024 ARTÍCULO WOS - SCOPUS AUTOR
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Evaluation of the bioactivity of Berberis microphylla G. Forst (Calafate) leaves infusion
FOOD BIOSCIENCE 2024 ARTÍCULO WOS - SCOPUS AUTOR
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Phase IIa randomized placebocontrolled clinical trial to evaluate the efficacy of bromhexine in combination with standard therapy in the early treatment of COVID-19 in primary care patients
REVISTA MEDICA DE CHILE 2024 ARTÍCULO WOS - SCIELO - SCOPUS AUTOR
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Understanding the Role of ATP Release through Connexins Hemichannels during Neurulation
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2023 ARTÍCULO WOS - SCOPUS AUTOR
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Modulation of GABAA receptors and of GABAergic synapses by the natural alkaloid gelsemine
FRONTIERS IN MOLECULAR NEUROSCIENCE 2023 ARTÍCULO WOS - SCOPUS AUTOR
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Partial Inhibition of Complex I Restores Mitochondrial Morphology and Mitochondria-ER Communication in Hippocampus of APP/PS1 Mice
CELLS 2023 ARTÍCULO WOS - SCOPUS AUTOR
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TG2 promotes amyloid beta aggregates: Impact on ER-mitochondria crosstalk, calcium homeostasis and synaptic function in Alzheimer's disease
BIOMEDICINE & PHARMACOTHERAPY 2023 ARTÍCULO WOS - SCOPUS AUTOR
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New Benzodihydrofuran Derivatives Alter the Amyloid beta Peptide Aggregation: Strategies To Develop New Anti-Alzheimer Drugs
ACS CHEMICAL NEUROSCIENCE 2023 ARTÍCULO WOS - SCOPUS AUTOR
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Neuroprotective Properties of Eudesmin on a Cellular Model of Amyloid-beta Peptide Toxicity
JOURNAL OF ALZHEIMERS DISEASE 2023 ARTÍCULO WOS - SCOPUS AUTOR
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Deciphering the role of PGC-1 alpha in neurological disorders: from mitochondrial dysfunction to synaptic failure
NEURAL REGENERATION RESEARCH 2022 REVIEW WOS - SCOPUS AUTOR
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Microglial Activation Modulated by P2X4R in Ischemia and Repercussions in Alzheimer's Disease
FRONTIERS IN PHYSIOLOGY 2022 REVIEW WOS - SCOPUS AUTOR
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Metabolic profile and antioxidant capacity of five Berberis leaves species: A comprehensive study to determine their potential as natural food or ingredient
FOOD RESEARCH INTERNATIONAL 2022 ARTÍCULO WOS - SCOPUS AUTOR
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Antiseizure medication in early nervous system development. Ion channels and synaptic proteins as principal targets
FRONTIERS IN PHARMACOLOGY 2022 ARTÍCULO WOS - SCOPUS AUTOR
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The Administration of the Synbiotic Lactobacillus bulgaricus 6c3 Strain, Inulin and Fructooligosaccharide Decreases the Concentrations of Indoxyl Sulfate and Kidney Damage in a Rat Model
TOXINS 2021 ARTÍCULO WOS - SCOPUS AUTOR
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Increased P2x2 receptors induced by amyloid-beta peptide participates in the neurotoxicity in alzheimer's disease
BIOMEDICINE & PHARMACOTHERAPY 2021 ARTÍCULO WOS - SCOPUS AUTOR
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Phenolic Compounds in Calafate Berries Encapsulated by Spray Drying: Neuroprotection Potential into the Ingredient
ANTIOXIDANTS 2021 ARTÍCULO WOS - SCOPUS AUTOR
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PrP(c) as a Transducer of Physiological and Pathological Signals
FRONTIERS IN MOLECULAR NEUROSCIENCE 2021 REVIEW WOS - SCOPUS AUTOR
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Exploring the Multi-Target Neuroprotective Chemical Space of Benzofuran Scaffolds: A New Strategy in Drug Development for Alzheimer's Disease
FRONTIERS IN PHARMACOLOGY 2020 REVIEW WOS - SCOPUS AUTOR
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Modulation of glycine receptor single-channel conductance by intracellular phosphorylation
SCIENTIFIC REPORTS 2020 ARTÍCULO WOS - SCOPUS AUTOR
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Changes in PGC-1 alpha/SIRT1 Signaling Impact on Mitochondrial Homeostasis in Amyloid-Beta Peptide Toxicity Model
FRONTIERS IN PHARMACOLOGY 2020 ARTÍCULO WOS - SCOPUS AUTOR
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Altered Glutaminase 1 Activity During Neurulation and Its Potential Implications in Neural Tube Defects
FRONTIERS IN PHARMACOLOGY 2020 ARTÍCULO WOS - SCOPUS AUTOR
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Inhibition of the Glycine Receptor alpha 3 Function by Colchicine
FRONTIERS IN PHARMACOLOGY 2020 ARTÍCULO WOS - SCOPUS AUTOR
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Stereospecific Inhibition of Ethanol Potentiation on Glycine Receptor by M554 Stereoisomers
JOURNAL OF CHEMICAL INFORMATION AND MODELING 2020 ARTÍCULO WOS - SCOPUS AUTOR
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Editorial: Celebrating 40 Years of the Chilean Society of Pharmacology
FRONTIERS IN PHARMACOLOGY 2020 OTRO TIPO EN REVISTA WOS - SCOPUS AUTOR
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17 Oxo Sparteine and Lupanine, Obtained from Cytisus scoparius, Exert a Neuroprotection against Soluble Oligomers of Amyloid-beta Toxicity by Nicotinic Acetylcholine Receptors
JOURNAL OF ALZHEIMERS DISEASE 2019 ARTÍCULO WOS - SCOPUS AUTOR
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Inhibitory Actions of Tropeines on the alpha 3 Glycine Receptor Function
FRONTIERS IN PHARMACOLOGY 2019 ARTÍCULO WOS - SCOPUS AUTOR
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Neuroprotective effects of EpoL against oxidative stress induced by soluble oligomers of A beta peptide
REDOX BIOLOGY 2019 ARTÍCULO WOS - SCOPUS AUTOR
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Large Intracellular Domain-Dependent Effects of Positive Allosteric Modulators on Glycine Receptors
ACS CHEMICAL NEUROSCIENCE 2019 ARTÍCULO WOS - SCOPUS AUTOR
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Exposure to UV-B Radiation Leads to Increased Deposition of Cell Wall-Associated Xerocomic Acid in Cultures of Serpula himantioides
APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2019 ARTÍCULO WOS - SCOPUS AUTOR
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Exploring the Role of P2X Receptors in Alzheimer's Disease
FRONTIERS IN PHARMACOLOGY 2019 ARTÍCULO WOS - SCOPUS AUTOR
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P2X receptor overexpression induced by soluble oligomers of amyloid beta peptide potentiates synaptic failure and neuronal dyshomeostasis in cellular models of alzheimer´s disease
NEUROPHARMACOLOGY 2018 ARTÍCULO WOS - SCOPUS AUTOR
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Prevention of Synaptic Alterations and Neurotoxic Effects of PAMAM Dendrimers by Surface Functionalization
NANOMATERIALS 2018 ARTÍCULO WOS - SCOPUS COAUTOR
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A Natural Benzofuran from the Patagonic Aleurodiscus vitellinus Fungus has Potent Neuroprotective Properties on a Cellular Model of Amyloid-beta Peptide Toxicity
JOURNAL OF ALZHEIMERS DISEASE 2018 ARTÍCULO WOS - SCOPUS COAUTOR
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Neuroprotective effect of a new variant of Epo nonhematopoietic against oxidative stress
REDOX BIOLOGY 2018 ARTÍCULO WOS - SCOPUS COAUTOR
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Cytotoxicity and in vivo plasma kinetic behavior of surface-functionalized PAMAM dendrimers
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE 2018 ARTÍCULO WOS - SCOPUS COAUTOR
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Neuroprotective effects of erythropoietin on neurodegenerative and ischemic brain diseases: the role of erythropoietin receptor
NEURAL REGENERATION RESEARCH 2017 REVIEW WOS - SCOPUS AUTOR
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ATP leakage induces P2XR activation and contributes to acute synaptic excitotoxiciw induced by soluble oligomers of beta-amyloid peptide in hippocampal neurons
NEUROPHARMACOLOGY 2016 ARTÍCULO WOS - SCOPUS AUTOR
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Functional modulation of glycine receptors by the alkaloid gelsemine
BRITISH JOURNAL OF PHARMACOLOGY 2016 ARTÍCULO WOS - SCOPUS COAUTOR
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Reversal of Ethanol-Induced Intoxication by a Novel Modulator of Gß¿ Potentiation of Glycine Receptor
JOURNAL OF BIOLOGICAL CHEMISTRY 2016 ARTÍCULO WOS - SCOPUS COAUTOR
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Bioequivalence Study of Two Hydrochlorothiazide Formulations after Oral Administration in Healthy Chilean Volunteers
JOURNAL OF PHARMACY AND PHARMACOLOGY (DAVID PUBLISHING) 2016 ARTÍCULO AUTOR
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Impact of mitichondrial dysfunction on neurodegenerative diseases: A key step on Alzheimer´s disease
JOURNAL OF SYSTEMS AND INTEGRATIVE NEUROSCIENCE 2016 ARTÍCULO AUTOR
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Neurotoxin-like compounds from the ichthyotoxic red tide alga Heterosigma akashiwo induce a TTX-like synaptic silencing in mammalian neurons
HARMFUL ALGAE 2015 ARTÍCULO WOS - SCOPUS AUTOR
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Neurotoxicity of AB Explained by its Association to Plasma Membranes
SIN REVISTA 2015 CAPÍTULO DE LIBRO COAUTOR -
Modulation of the neuronal network activity by P2X receptors and their involvement in neurological disorders
PHARMACOLOGICAL RESEARCH 2015 ARTÍCULO WOS - SCOPUS AUTOR
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Modulation of Neuronal Nicotinic Receptor by Quinolizidine Alkaloids Causes Neuroprotection on a Cellular Alzheimer Model
JOURNAL OF ALZHEIMERS DISEASE 2014 ARTÍCULO WOS - SCOPUS AUTOR
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Copper-uptake is critical for the down regulation of synapsin and dynamin induced by neocuproine: modulation of synaptic activity in hippocampal neurons
FRONTIERS IN AGING NEUROSCIENCE 2014 ARTÍCULO WOS - SCOPUS COAUTOR
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Neuroactive alkaloids that modulate the neuronal nicotinic receptor and provide neuroprotection in an Alzheimer's disease model: the case of Teline monspessulana
NEURAL REGENERATION RESEARCH 2014 OTRO TIPO EN REVISTA WOS - SCOPUS AUTOR
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Synaptic Silencing and Plasma Membrane Dyshomeostasis induced by Amyloid-b peptide are Prevented by Aristotelia chilensis Enriched Extract
JOURNAL OF ALZHEIMERS DISEASE 2012 ARTÍCULO WOS - SCOPUS AUTOR -
Inhibition of the Ethanol-induced Potentiation of a1 Glycine Receptor by a Small Peptide That Interferes with Gby Binding
JOURNAL OF BIOLOGICAL CHEMISTRY 2012 ARTÍCULO WOS - SCOPUS COAUTOR -
Inhibitory activities on Mammalian Central Nervous System Receptors and Computational Studies of Three Sesquiterpene lactones from Coraria ruscifolia subsp. Ruscifolia
CHEMICAL & PHARMACEUTICAL BULLETIN 2011 ARTÍCULO WOS - SCOPUS COAUTOR -
Cloning and Spatiotemporal Expression of RIC-8 in Xenopus embryogenesis
GENE EXPRESSION PATTERNS 2011 ARTÍCULO WOS - SCOPUS COAUTOR -
Synaptic failure and adenosine triphosphate imbalance induced by amyloid-B aggregates are prevented by blueberry-enriched polyphenol extract
JOURNAL OF NEUROSCIENCE RESEARCH 2011 ARTÍCULO WOS - SCOPUS AUTOR -
Impacto del Entrenamiento del Balance a Través de Realidad Virtual en una Población de Adultos Mayores
INTERNATIONAL JOURNAL OF MORPHOLOGY 2010 ARTÍCULO WOS - DIRECTORIO - SCIELO - SCOPUS COAUTOR -
Potentiation and Inhibition of Glycine Receptors by Tutin
NEUROPHARMACOLOGY 2010 ARTÍCULO WOS - SCOPUS AUTOR -
Impact of balance training with a virtual reality in elderly
INTERNATIONAL JOURNAL OF MORPHOLOGY 2010 ARTÍCULO WOS - DIRECTORIO - SCIELO - SCOPUS AUTOR -
Blockade of Ethanol-Induced Potentiation of Glycine Receptors by a Peptide that Interferes with Gbetasigma Binding
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 2009 ARTÍCULO WOS - SCOPUS COAUTOR -
Inhibitory Effects of Tutin on Glycine Receptors in Spinal Neurons
EUROPEAN JOURNAL OF PHARMACOLOGY 2007 ARTÍCULO WOS - SCOPUS AUTOR -
Tight Coupling of the t-SNARE and Calcium Channel Microdomains in Adrenomedullary Slices and not in Cultured Chramaffin Cells
CELL CALCIUM 2007 ARTÍCULO WOS - SCOPUS COAUTOR -
Historical and Current Perspectives of Neuroactive Compounds Derived from Latin America
JOURNAL OF MEDICINAL CHEMISTRY 2006 ARTÍCULO WOS - SCOPUS COAUTOR