MARÍA DE LOS ANGELES GARCÍA ROBLES – Académico UdeC

Tanycyte-derived lactate activates astrocytic HCAR1 to modulate glutamatergic signaling and POMC neuron excitability

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2026 ARTÍCULO WOS - SCOPUS AUTOR

Knocking down the neuronal lactate transporter MCT2 in the arcuate nucleus of female rats increases food intake and body weight

SCIENTIFIC REPORTS 2025 ARTÍCULO WOS - SCOPUS AUTOR

Poly (I:C)-induced inflammation requires the activation of toll-like receptor 3/Ca2+/CaMKII/pannexin 1-dependent signaling

THERANOSTICS 2025 ARTÍCULO WOS - SCOPUS AUTOR

Targeting the immunoproteasome in hypothalamic neurons as a novel therapeutic strategy for high-fat diet-induced obesity and metabolic dysregulation

JOURNAL OF NEUROINFLAMMATION 2024 ARTÍCULO WOS - SCOPUS AUTOR

Regulatory T cells administration reduces anxiety-like behavior in mice submitted to chronic restraint stress

FRONTIERS IN CELLULAR NEUROSCIENCE 2024 ARTÍCULO WOS - SCOPUS AUTOR

Enhancing late postmortem interval prediction: a pilot study integrating proteomics and machine learning to distinguish human bone remains over 15 years

BIOLOGICAL RESEARCH 2024 ARTÍCULO WOS - SCIELO - SCOPUS AUTOR

Lactate: an alternative pathway for the immunosuppressive properties of mesenchymal stem/stromal cells

STEM CELL RESEARCH & THERAPY 2023 ARTÍCULO WOS - SCOPUS AUTOR

Association of the dopamine D2 receptor rs1800497 polymorphism with food addiction, food reinforcement, and eating behavior in Chilean adults

EATING AND WEIGHT DISORDERS-STUDIES ON ANOREXIA BULIMIA AND OBESITY 2022 ARTÍCULO WOS - SCOPUS AUTOR

GKRP-dependent modulation of feeding behavior by tanycyte-released monocarboxylates

THERANOSTICS 2022 ARTÍCULO WOS - SCOPUS AUTOR

New Insights into the Determinants of Specificity in Human Type I Arginase: Generation of a Mutant That Is Only Active with Agmatine as Substrate

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2022 ARTÍCULO WOS - SCOPUS AUTOR

A Short-Term Sucrose Diet Impacts Cell Proliferation of Neural Precursors in the Adult Hypothalamus

NUTRIENTS 2022 ARTÍCULO WOS - SCOPUS AUTOR

GLUT2 expression by glial fibrillary acidic protein-positive tanycytes is required for promoting feeding-response to fasting

SCIENTIFIC REPORTS 2022 ARTÍCULO WOS - SCOPUS AUTOR

Neuroprotective and Neurotoxic Effects of Glial-Derived Exosomes

FRONTIERS IN CELLULAR NEUROSCIENCE 2022 REVIEW WOS - SCOPUS AUTOR

The ATP synthase inhibition induces an AMPK-dependent glycolytic switch of mesenchymal stem cells that enhances their immunotherapeutic potential

THERANOSTICS 2021 ARTÍCULO WOS - SCOPUS AUTOR

Purinergic signaling in tanycytes and its contribution to nutritional sensing

PURINERGIC SIGNALLING 2021 REVIEW WOS - SCOPUS AUTOR

Lactate activates hypothalamic POMC neurons by intercellular signaling

SCIENTIFIC REPORTS 2021 ARTÍCULO WOS - SCOPUS AUTOR

Functional analysis of the Mn2+ requirement in the catalysis of ureohydrolases arginase and agmatinase - a historical perspective

JOURNAL OF INORGANIC BIOCHEMISTRY 2020 REVIEW WOS - SCOPUS AUTOR

Inhibition of hypothalamic MCT4 and MCT1-MCT4 Expressions affects food intake and alters orexigenic anorexigenic neuropeptide expressions

MOLECULAR NEUROBIOLOGY 2020 ARTÍCULO WOS - SCOPUS AUTOR

Insights on the participation of Glu256 and Asp204 in the oligomeric structure and cooperative effects of human arginase type I

JOURNAL OF STRUCTURAL BIOLOGY 2020 ARTÍCULO WOS - SCOPUS AUTOR

HIF1 alpha-dependent metabolic reprogramming governs mesenchymal stem/stromal cell immunoregulatory functions

FASEB JOURNAL 2020 ARTÍCULO WOS - SCOPUS AUTOR

Insights into the Mn2+ Binding Site in the Agmatinase-Like Protein (ALP): A Critical Enzyme for the Regulation of Agmatine Levels in Mammals

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2020 ARTÍCULO WOS - SCOPUS AUTOR

PPAR beta/delta-dependent MSC metabolism determines their immunoregulatory properties

SCIENTIFIC REPORTS 2020 ARTÍCULO WOS - SCOPUS AUTOR

Editorial: Involvement of Tanycytes in the Neuroendocrine Control of Energy Homeostasis

FRONTIERS IN ENDOCRINOLOGY 2020 OTRO TIPO EN REVISTA WOS - SCOPUS AUTOR

Tympanic Membrane Rupture During Stereotaxic Surgery Disturbs the Normal Feeding Behavior in Rats

FRONTIERS IN BEHAVIORAL NEUROSCIENCE 2020 ARTÍCULO WOS - SCOPUS AUTOR

The FGF2-induced tanycyte proliferation involves a connexin 43 hemichannel/purinergic-dependent pathway

JOURNAL OF NEUROCHEMISTRY 2020 ARTÍCULO WOS - SCOPUS AUTOR

When a Little Bit More Makes the Difference: Expression Levels of GKRP Determines the Subcellular Localization of GK in Tanycytes

FRONTIERS IN NEUROSCIENCE 2019 ARTÍCULO WOS - SCOPUS AUTOR

Glucose Increase DAGL alpha Levels in Tanycytes and Its Inhibition Alters Orexigenic and Anorexigenic Neuropeptides Expression in Response to Glucose

FRONTIERS IN ENDOCRINOLOGY 2019 ARTÍCULO WOS - SCOPUS AUTOR

Glial hypothalamic inhibition of GLUT2 expression alters satiety, impacting eating behavior

GLIA 2018 ARTÍCULO WOS - SCOPUS AUTOR

Metabolic strategies for the degradation of the neuromodulator agmatine in mammals

METABOLISM-CLINICAL AND EXPERIMENTAL 2018 REVIEW WOS - SCOPUS AUTOR

SALL2 represses cyclins D1 and E1 expression and restrains G1/S cell cycle transition and cancer-related phenotypes

MOLECULAR ONCOLOGY 2018 ARTÍCULO WOS - SCOPUS AUTOR

Connexin-43 Gap Junctions Are Responsible for the Hypothalamic Tanycyte-Coupled Network

FRONTIERS IN CELLULAR NEUROSCIENCE 2018 ARTÍCULO WOS - SCOPUS AUTOR

Mammalian agmatinases constitute unusual members in the family of Mn2+-dependent ureahydrolases

JOURNAL OF INORGANIC BIOCHEMISTRY 2017 ARTÍCULO WOS - SCOPUS COAUTOR

Hypothalamic Neurogenesis as an Adaptive Metabolic Mechanism

FRONTIERS IN NEUROSCIENCE 2017 REVIEW WOS - SCOPUS AUTOR

Adenovirus-mediated suppression of hypothalamic glucokinase affects feeding behavior

SCIENTIFIC REPORTS 2017 ARTÍCULO WOS - SCOPUS AUTOR

Molecular Characteristics, Regulation, and Function of Monocarboxylate.

SIN REVISTA 2017 CAPÍTULO DE LIBRO COAUTOR

Cloning of two LIMCH1 isoforms: characterization of their distribution in rat brain and their agmatinase activity

HISTOCHEMISTRY AND CELL BIOLOGY 2016 ARTÍCULO WOS - SCOPUS COAUTOR

Inhibition of hypothalamic MCT1 expression increases food intake and alters orexigenic and anorexigenic neuropeptide expression

SCIENTIFIC REPORTS 2016 ARTÍCULO WOS - SCOPUS AUTOR

Monocarboxylate transporters (MCTs) and their role in hypothalamic glucose detection

MOJ CELL SCIENCE & REPORT 2016 ARTÍCULO AUTOR

Insight on the interaction of an agmatinase-like protein with Mn (2+) activator ions

JOURNAL OF INORGANIC BIOCHEMISTRY 2015 ARTÍCULO WOS - SCOPUS COAUTOR

The role of Tanycytes in Hypothalamic Glucosensing

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 2015 ARTÍCULO WOS - SCOPUS AUTOR

Dynamic Localization of Glucokinase adn regulatory Protein Hypothalamic Tanycytes

PLOS ONE 2014 ARTÍCULO WOS - SCOPUS AUTOR

SVCT2 transporter expression is post-natally induced in cortical neurons and its function is regulated by its short isoform

JOURNAL OF NEUROCHEMISTRY 2014 ARTÍCULO WOS - SCOPUS COAUTOR

Dynamic expression of the sodium-vitamin C co-transporters, SVCT1 and SVCT2, during perinatal kidney development

HISTOCHEMISTRY AND CELL BIOLOGY 2013 ARTÍCULO WOS - SCOPUS COAUTOR

MCT2 Expression and Lactate Influx in Anorexigenic and Orexigenic Neurons of the Arcuate Nucleus

PLOS ONE 2013 ARTÍCULO WOS - SCOPUS AUTOR

Human choroid plexus papilloma cells efficiently transport glucose and vitamin C

JOURNAL OF NEUROCHEMISTRY 2013 ARTÍCULO WOS - SCOPUS COAUTOR

Superoxide-dependent uptake of vitamin C in human glioma cells

JOURNAL OF NEUROCHEMISTRY 2013 ARTÍCULO WOS - SCOPUS COAUTOR

Clinical and experimental approaches to knee cartilage lesion repair and mesenchymal stem cell chondrocyte differentiation

BIOLOGICAL RESEARCH 2013 ARTÍCULO WOS - SCIELO - SCOPUS COAUTOR

Glucose Increases Intracellular Free Ca2+ in Tanycytes via ATP Released Through Connexin 43 Hemichannels

GLIA 2012 ARTÍCULO WOS - SCOPUS AUTOR

Control cerebral de la homeostasis de la glucosa. Interacción Glia-Neurona

JOURNAL OF BIOMEDICAL SCIENCE 2012 ARTÍCULO WOS - SCOPUS AUTOR

Glucose Transporter 1 and Monocarboxylate Transporters 1,2 and 4 Localization within the Glial Cells of Shark Blood-Brain-Barriers

PLOS ONE 2012 ARTÍCULO WOS - SCOPUS COAUTOR

Typical and atypical stem cells in the brain, vitamin C effect and neuropathology

BIOLOGICAL RESEARCH 2012 ARTÍCULO WOS - SCIELO - SCOPUS COAUTOR

MCT Expression and Lactate Influx/Efflux in Tanycytes Involved in Glia-Neuron Metabolic Interaction

PLOS ONE 2011 ARTÍCULO WOS - SCOPUS AUTOR

Expression and distribution of facilitative glucosa (Gluts) and monocarboxylate/H+ (MCTs) transporters in rat olfatoty epithelia

CHEMICAL SENSES 2011 ARTÍCULO WOS - SCOPUS COAUTOR

Insulin regulates GLUT-1 medianted glucose transport in MG-63 human osteosarcoma

JOURNAL OF CELLULAR PHYSIOLOGY 2011 ARTÍCULO WOS - SCOPUS COAUTOR

Expression and Localization of an Agmatinase-Like Protein in the Rat Brain

HISTOCHEMISTRY AND CELL BIOLOGY 2010 ARTÍCULO WOS - SCOPUS COAUTOR

Glial Glucokinase Expression in Adult and Post-Natal Development of the Hypothalamic Region

ASN NEURO 2010 ARTÍCULO WOS - SCOPUS AUTOR

The Na+-Dependent L-Ascorbic Acid Transporter SVCT2 Expressed in Brainstem Cells, Neurons, and Neuroblastoma Cells is Inhibited by Flavonoids

JOURNAL OF NEUROCHEMISTRY 2009 ARTÍCULO WOS - SCOPUS COAUTOR

Glucose Transporters in Sex Steroid Hormone Related Cancer

CURRENT VASCULAR PHARMACOLOGY 2009 ARTÍCULO WOS - SCOPUS COAUTOR

Nutritional Channels in Breast Cancer

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 2008 ARTÍCULO WOS - SCOPUS COAUTOR

Differential Distribution of the Sodium-Vitamin C Cotransporter-1 Along the Proximal Tubule of the Mouse and Human Kidney

KIDNEY INTERNATIONAL 2008 ARTÍCULO WOS - SCOPUS COAUTOR

Regulation of GLUT3 and Glucose Uptake by the cAMP Signalling Pathway in the Breast Cancer Cell Line ZR-75

JOURNAL OF CELLULAR PHYSIOLOGY 2008 ARTÍCULO WOS - SCOPUS COAUTOR

Intracellular Ascorbic Acid Inhibits Transport of Glucose by Neurons, but not by Astrocytes

JOURNAL OF NEUROCHEMISTRY 2007 ARTÍCULO WOS - SCOPUS COAUTOR

Differential Subcellular Distribution of Glucose Transporters CLUT1-6 and GLUT9 in Human Cancer: Ultrastructural Localization of GLUT1 and LUT5 in Breast Tumor Tissues

JOURNAL OF CELLULAR PHYSIOLOGY 2006 ARTÍCULO WOS - SCOPUS COAUTOR

Ependymal Cell Di Erentiation and GLUT1 Expression is a Synchronous Process in the Ventricular Wall

NEUROCHEMICAL RESEARCH 2005 ARTÍCULO WOS - SCOPUS COAUTOR

Sodium Vitamin C Cotransporter SVCT2 Is Expressed in Hypothalamic Glial Cells

GLIA 2005 ARTÍCULO WOS - SCOPUS COAUTOR

Novel Expression of Liver FBPase in Langerhans Islets of Human and Rat Pancreas

JOURNAL OF CELLULAR PHYSIOLOGY 2005 ARTÍCULO WOS - SCOPUS COAUTOR

Cytogenetic Damage in Female Chilean Agricultural Workers Exposed to Mixtures of Pesticides

ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 2005 ARTÍCULO WOS - SCOPUS COAUTOR

Vitamin C Uptake and Recycling Among Normal and tumor Cells From the Central Nervous System

JOURNAL OF NEUROSCIENCE RESEARCH 2005 ARTÍCULO WOS - SCOPUS COAUTOR

Regulation by Insulin and Insulin-like Growth Factor of 2-Deoxyglucose Uptake in Primary Ependymal Cell Cultures

NEUROCHEMICAL RESEARCH 2004 ARTÍCULO WOS - SCOPUS COAUTOR

Hypothalamic Ependymal-glial Cells Express the Glucose Transporter GLUT2, a Protein Involved in Glucose Sensing

JOURNAL OF NEUROCHEMISTRY 2003 ARTÍCULO WOS - SCOPUS AUTOR

Estrogen and Progesterone Up-Regulate Glucose Transporter Expression in ZR-75-1 Human Breast Cancer Cells

ENDOCRINOLOGY 2003 ARTÍCULO WOS - SCOPUS COAUTOR

Human Brain Synembryn Interacts with Gsa and Gqa and Is translocated to the Plasma Membrane in Response to Isoproterenol and Carbachol

JOURNAL OF CELLULAR PHYSIOLOGY 2003 ARTÍCULO WOS - SCOPUS COAUTOR