FS
Académico · Postgrado UdeC
FABIÁN JOSUE SEGOVIA MIRANDA
Doctor en Ciencias Biológicas m/ Biol. Celular y Molecular
Pontificia Universidad Católica de Chile
fabiansegovia@udec.cl-
NucVerse3D: generalizable 3D nuclear instance segmentation across heterogeneous microscopy modalities
SCIENTIFIC REPORTS 2026 ARTÍCULO WOS - SCOPUS AUTOR
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Endogenous Galectin-8 protects against Th17 infiltration and fibrosis following acute kidney injury
MOLECULAR MEDICINE 2025 ARTÍCULO WOS - SCOPUS AUTOR
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An Open-source Protocol for Deep Learning-based Segmentation of Tubular Structures in 3D Fluorescence Microscopy Images
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS 2025 ARTÍCULO WOS - SCOPUS AUTOR
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Phenotypic characterization of liver tissue heterogeneity through a next-generation 3D single-cell atlas
SCIENTIFIC REPORTS 2024 ARTÍCULO WOS - SCOPUS AUTOR
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Virtual tissue microstructure reconstruction across species using generative deep learning
PLOS ONE 2024 ARTÍCULO WOS - SCOPUS AUTOR
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Targeting the immunoproteasome in hypothalamic neurons as a novel therapeutic strategy for high-fat diet-induced obesity and metabolic dysregulation
JOURNAL OF NEUROINFLAMMATION 2024 ARTÍCULO WOS - SCOPUS AUTOR
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Maternal regulation of the vertebrate oocyte-to-embryo transition
PLOS GENETICS 2024 ARTÍCULO WOS - SCOPUS AUTOR
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Neuronal surface P antigen (NSPA) modulates postsynaptic NMDAR stability through ubiquitination of tyrosine phosphatase PTPMEG
BMC BIOLOGY 2020 ARTÍCULO WOS - SCOPUS AUTOR
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Quantification of nematic cell polarity in three-dimensional tissues
PLOS COMPUTATIONAL BIOLOGY 2020 ARTÍCULO WOS - SCOPUS AUTOR
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Liquid-crystal organization of liver tissue
ELIFE 2019 ARTÍCULO WOS - SCOPUS AUTOR
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Three-dimensional spatially resolved geometrical and functional models of human liver tissue reveal new aspects of NAFLD progression
NATURE MEDICINE 2019 ARTÍCULO WOS - SCOPUS AUTOR
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Content-aware image restoration: pushing the limits of fluorescence microscopy
NATURE METHODS 2018 ARTÍCULO WOS - SCOPUS AUTOR
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Galectin-8 Favors the Presentation of Surface-Tethered Antigens by Stabilizing the B Cell Immune Synapse
CELL REPORTS 2018 ARTÍCULO WOS - SCOPUS AUTOR
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A Predictive 3D Multi-Scale Model of Biliary Fluid Dynamics in the Liver Lobule
CELL SYSTEMS 2017 ARTÍCULO WOS - SCOPUS AUTOR
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Galectin-8 as an immunosuppressor in experimental autoimmune encephalomyelitis and a target of human early prognostic antibodies in multiple sclerosis
PLOS ONE 2017 ARTÍCULO WOS - SCOPUS AUTOR
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Anti-Ribosomal P Protein Autoantibodies From Patients With Neuropsychiatric Lupus Impair Memory in Mice
ARTHRITIS & RHEUMATOLOGY 2015 ARTÍCULO WOS - SCOPUS AUTOR
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Pathogenicity of Lupus Anti-Ribosomal P Antibodies: Role of Cross-Reacting Neuronal Surface P Antigen in Glutamatergic Transmission and Plasticity in a Mouse Model
ARTHRITIS & RHEUMATOLOGY 2015 ARTÍCULO WOS - SCOPUS AUTOR
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A versatile pipeline for the multi-scale digital reconstruction and quantitative analysis of 3D tissue architecture
ELIFE 2015 ARTÍCULO WOS - SCOPUS AUTOR
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Syndecan-1 regulates BMP signaling and dorso-ventral patterning of the ectoderm during early Xenopus development
DEVELOPMENTAL BIOLOGY 2009 ARTÍCULO WOS - SCOPUS AUTOR
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Antiphospholipid syndrome: a comprehensive review of a complex and multisystemic disease
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY 2009 REVIEW WOS - SCOPUS AUTOR -
Increased concentrations of soluble vascular cell adhesion molecule-1 and soluble CD40L in subjects with metabolic syndrome
MOLECULAR MEDICINE REPORTS 2009 ARTÍCULO WOS - SCOPUS AUTOR
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Increased concentration of plasminogen activator inhibitor-1 and fibrinogen in individuals with metabolic syndrome
MOLECULAR MEDICINE REPORTS 2009 ARTÍCULO WOS - SCOPUS AUTOR
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Heme iron uptake by Caco-2 cells is a saturable, temperature sensitive and modulated by extracellular pH and potassium
BIOLOGICAL TRACE ELEMENT RESEARCH 2008 ARTÍCULO WOS - SCOPUS AUTOR