JG
Académico · Postgrado UdeC
JOSE LEONARDO GUZMAN GONZALEZ
Doctor en Ciencias Biológicas
Universidad de Concepción
joseguzman@udec.cl-
Visible-light-triggered halloysite nanotubes modified with Chlorin e6 and Polyethylene glycol-Folic Acid for site-specific chemo-photodynamic therapy
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY 2026 ARTÍCULO WOS - SCOPUS AUTOR
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Enhancement of octreotide antiproliferative activity by PEGylated PAMAM dendrimers delivery
JOURNAL OF APPLIED POLYMER SCIENCE 2024 ARTÍCULO WOS - SCOPUS AUTOR
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Cell internalization kinetics and surface charge accessibility of surface-modified PAMAM dendrimers
ORGANIC & BIOMOLECULAR CHEMISTRY 2023 ARTÍCULO WOS - SCOPUS AUTOR
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A highly conserved plant volatile odorant receptor detects a sex pheromone component of the greater wax moth, Galleria mellonella (Lepidoptera: Pyralidae)
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY 2023 ARTÍCULO WOS - SCOPUS AUTOR
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Polyamidoamine dendrimers of the third generation-chlorin e6 nanoconjugates: Nontoxic hybrid polymers with photodynamic activity
JOURNAL OF APPLIED POLYMER SCIENCE 2022 ARTÍCULO WOS - SCOPUS AUTOR
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Rational design and in vitro evaluation of novel peptides binding to neuroligin-1 for synaptic targeting
JOURNAL OF CHEMICAL INFORMATION AND MODELING 2020 ARTÍCULO WOS - SCOPUS AUTOR
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Visible-light-responsive folate-conjugated titania and alumina nanotubes for photodynamic therapy applications
JOURNAL OF MATERIALS SCIENCE 2020 ARTÍCULO WOS - SCOPUS AUTOR
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Modulation of glycine receptor single-channel conductance by intracellular phosphorylation
SCIENTIFIC REPORTS 2020 ARTÍCULO WOS - SCOPUS AUTOR
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Changes in PGC-1 alpha/SIRT1 Signaling Impact on Mitochondrial Homeostasis in Amyloid-Beta Peptide Toxicity Model
FRONTIERS IN PHARMACOLOGY 2020 ARTÍCULO WOS - SCOPUS AUTOR
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Mechanism-Based Rational Discovery and In Vitro Evaluation of Novel Microtubule Stabilizing Agents with Non-Taxol-Competitive Activity
JOURNAL OF CHEMICAL INFORMATION AND MODELING 2020 ARTÍCULO WOS - SCOPUS AUTOR
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Altered Glutaminase 1 Activity During Neurulation and Its Potential Implications in Neural Tube Defects
FRONTIERS IN PHARMACOLOGY 2020 ARTÍCULO WOS - SCOPUS AUTOR
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Inhibition of the Glycine Receptor alpha 3 Function by Colchicine
FRONTIERS IN PHARMACOLOGY 2020 ARTÍCULO WOS - SCOPUS AUTOR
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Polyamidoamine-based nanovector for the efficient delivery of methotrexate to U87 glioma cells
NANOMEDICINE 2020 ARTÍCULO WOS - SCOPUS AUTOR
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Stereospecific Inhibition of Ethanol Potentiation on Glycine Receptor by M554 Stereoisomers
JOURNAL OF CHEMICAL INFORMATION AND MODELING 2020 ARTÍCULO WOS - SCOPUS AUTOR
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17 Oxo Sparteine and Lupanine, Obtained from Cytisus scoparius, Exert a Neuroprotection against Soluble Oligomers of Amyloid-beta Toxicity by Nicotinic Acetylcholine Receptors
JOURNAL OF ALZHEIMERS DISEASE 2019 ARTÍCULO WOS - SCOPUS COAUTOR
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Inhibitory Actions of Tropeines on the alpha 3 Glycine Receptor Function
FRONTIERS IN PHARMACOLOGY 2019 ARTÍCULO WOS - SCOPUS AUTOR
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Large Intracellular Domain-Dependent Effects of Positive Allosteric Modulators on Glycine Receptors
ACS CHEMICAL NEUROSCIENCE 2019 ARTÍCULO WOS - SCOPUS AUTOR
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P2X receptor overexpression induced by soluble oligomers of amyloid beta peptide potentiates synaptic failure and neuronal dyshomeostasis in cellular models of alzheimer´s disease
NEUROPHARMACOLOGY 2018 ARTÍCULO WOS - SCOPUS COAUTOR
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Prevention of Synaptic Alterations and Neurotoxic Effects of PAMAM Dendrimers by Surface Functionalization
NANOMATERIALS 2018 ARTÍCULO WOS - SCOPUS AUTOR
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Partially PEGylated PAMAM dendrimers as solubility enhancers of Silybin
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY 2018 ARTÍCULO WOS - SCOPUS COAUTOR
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Cytotoxicity and in vivo plasma kinetic behavior of surface-functionalized PAMAM dendrimers
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE 2018 ARTÍCULO WOS - SCOPUS COAUTOR
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Polyamido amine (PAMAM)-grafted magnetic nanotubes as emerging platforms for the delivery and sustained release of silibinin
JOURNAL OF MATERIALS SCIENCE 2017 ARTÍCULO WOS - SCOPUS COAUTOR
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ATP leakage induces P2XR activation and contributes to acute synaptic excitotoxiciw induced by soluble oligomers of beta-amyloid peptide in hippocampal neurons
NEUROPHARMACOLOGY 2016 ARTÍCULO WOS - SCOPUS COAUTOR
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Functional modulation of glycine receptors by the alkaloid gelsemine
BRITISH JOURNAL OF PHARMACOLOGY 2016 ARTÍCULO WOS - SCOPUS COAUTOR
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PAMAM-Conjugated Alumina Nanotubes as Novel Noncytotoxic Nanocarriers with Enhanced Drug Loading and Releasing Performances
MACROMOLECULAR CHEMISTRY AND PHYSICS 2016 ARTÍCULO WOS - SCOPUS COAUTOR
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Reversal of Ethanol-Induced Intoxication by a Novel Modulator of Gß¿ Potentiation of Glycine Receptor
JOURNAL OF BIOLOGICAL CHEMISTRY 2016 ARTÍCULO WOS - SCOPUS AUTOR
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Mechanism of PAMAM Dendrimers Internationalization in Hippocampal Neurons
MOLECULAR PHARMACEUTICS 2016 ARTÍCULO WOS - SCOPUS AUTOR
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Impact of mitichondrial dysfunction on neurodegenerative diseases: A key step on Alzheimer´s disease
JOURNAL OF SYSTEMS AND INTEGRATIVE NEUROSCIENCE 2016 ARTÍCULO COAUTOR
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PAMAM-grafted TiO2 nanotubes as novel versatile materials for drug delivery applications
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS 2016 ARTÍCULO WOS - SCOPUS COAUTOR
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Evidence for a-helices in the large intracellular domain mediating modulation of the alpha 1 glycine receptor by ethanol and GBy
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 2015 ARTÍCULO WOS - SCOPUS COAUTOR
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Dendrimer nanocarriers drug action: perspective for neuronal pharmacology
NEURAL REGENERATION RESEARCH 2015 ARTÍCULO WOS - SCOPUS AUTOR
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Ethanol effects on glycinergic transmission: From molecular pharmacology to behavior responses
PHARMACOLOGICAL RESEARCH 2015 ARTÍCULO WOS - SCOPUS COAUTOR
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Modulation of Neuronal Nicotinic Receptor by Quinolizidine Alkaloids Causes Neuroprotection on a Cellular Alzheimer Model
JOURNAL OF ALZHEIMERS DISEASE 2014 ARTÍCULO WOS - SCOPUS COAUTOR
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Synaptic Silencing and Plasma Membrane Dyshomeostasis induced by Amyloid-b peptide are Prevented by Aristotelia chilensis Enriched Extract
JOURNAL OF ALZHEIMERS DISEASE 2012 ARTÍCULO WOS - SCOPUS COAUTOR -
Inhibition of the Ethanol-induced Potentiation of a1 Glycine Receptor by a Small Peptide That Interferes with Gby Binding
JOURNAL OF BIOLOGICAL CHEMISTRY 2012 ARTÍCULO WOS - SCOPUS AUTOR -
Inhibitory activities on Mammalian Central Nervous System Receptors and Computational Studies of Three Sesquiterpene lactones from Coraria ruscifolia subsp. Ruscifolia
CHEMICAL & PHARMACEUTICAL BULLETIN 2011 ARTÍCULO WOS - SCOPUS COAUTOR -
Molecular Requirements for Ethanol Differential Allosteric Modulation of Glycine Receptors Based on Slective Gbetagamma Modulation
JOURNAL OF BIOLOGICAL CHEMISTRY 2010 ARTÍCULO WOS - SCOPUS COAUTOR -
Blockade of Ethanol-Induced Potentiation of Glycine Receptors by a Peptide that Interferes with Gbetasigma Binding
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 2009 ARTÍCULO WOS - SCOPUS AUTOR -
Inhibitory Effects of Tutin on Glycine Receptors in Spinal Neurons
EUROPEAN JOURNAL OF PHARMACOLOGY 2007 ARTÍCULO WOS - SCOPUS COAUTOR -
A Gby Stimulated Adenylyl Cyclase is Involved in Xenopus Laevis Oocyte Maturation
JOURNAL OF CELLULAR PHYSIOLOGY 2005 ARTÍCULO WOS - SCOPUS COAUTOR