LUIS GERARDO AGUAYO HERNÁNDEZ – Académico UdeC

Allosteric modulation and direct activation of glycine receptors by a tricyclic sulfonamide.

SCIENTIFIC REPORTS 2025 ARTÍCULO WOS - SCOPUS AUTOR

Synaptic and synchronic impairments in subcortical brain regions associated with early non-cognitive dysfunction in Alzheimer's disease

NEURAL REGENERATION RESEARCH 2025 REVIEW WOS - SCOPUS AUTOR

Alterations in neuronal excitability and AMPA-mediated neurotransmission in an APP/PS1 neuronal culture model derived from nucleus accumbens

JOURNAL OF ALZHEIMERS DISEASE 2025 ARTÍCULO WOS - SCOPUS AUTOR

Changes in the Properties of Ethanol-Sensitive Molecular Targets During Maturation and Aging

SIN REVISTA 2025 CAPÍTULO DE LIBRO AUTOR

Molecular Docking Analysis at the Human a7-nAChR and Proliferative and Evoked-Calcium Changes in SH-SY5Y Cells by Imidacloprid and Acetamiprid Insecticides

NEUROTOXICITY RESEARCH 2024 ARTÍCULO WOS - SCOPUS AUTOR

Molecular Pharmacology of Gelsemium Alkaloids on Inhibitory Receptors

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2024 ARTÍCULO WOS - SCOPUS AUTOR

Changes in ethanol effects in knock-in mice expressing ethanol insensitive alpha1 and alpha2 glycine receptor subunits

LIFE SCIENCES 2024 ARTÍCULO WOS - SCOPUS AUTOR

Loss of glycine receptors in the nucleus accumbens and ethanol reward in an Alzheimer's Disease mouse model

PROGRESS IN NEUROBIOLOGY 2024 ARTÍCULO WOS - SCOPUS AUTOR

Aging in nucleus accumbens and its impact on alcohol use disorders

ALCOHOL 2023 ARTÍCULO WOS - SCOPUS AUTOR

Overexpression of wild type glycine alpha 1 subunit rescues ethanol sensitivity in accumbal receptors and reduces binge drinking in mice

NEUROPSYCHOPHARMACOLOGY 2023 ARTÍCULO WOS - SCOPUS AUTOR

Modulation of GABAA receptors and of GABAergic synapses by the natural alkaloid gelsemine

FRONTIERS IN MOLECULAR NEUROSCIENCE 2023 ARTÍCULO WOS - SCOPUS AUTOR

Neurocytotoxicity of imidacloprid- and acetamiprid-based comercial insecticides over the differentiation of SH-SY5Y neuroblastoma cells

HELIYON 2023 ARTÍCULO WOS - SCOPUS AUTOR

GKRP-dependent modulation of feeding behavior by tanycyte-released monocarboxylates

THERANOSTICS 2022 ARTÍCULO WOS - SCOPUS AUTOR

Involvement of cholesterol and ß-amyloid in the initiation and progression of Alzheimer's disease

SIN REVISTA 2022 CAPÍTULO DE LIBRO AUTOR

Boldine Attenuates Synaptic Failure and Mitochondrial Deregulation in Cellular Models of Alzheimer's Disease

FRONTIERS IN NEUROSCIENCE 2021 ARTÍCULO WOS - SCOPUS AUTOR

Synaptic dysregulation and hyperexcitability induced by intracellular amyloid beta oligomers

AGING CELL 2021 ARTÍCULO WOS - SCOPUS AUTOR

Contribution of GlyR alpha 3 Subunits to the Sensitivity and Effect of Ethanol in the Nucleus Accumbens

FRONTIERS IN MOLECULAR NEUROSCIENCE 2021 ARTÍCULO WOS - SCOPUS AUTOR

The stimulatory effects of intracellular a-synuclein on synaptic transmission are attenuated by 2-octahydroisoquinolin-2(1h)-ylethanamine

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021 ARTÍCULO WOS - SCOPUS AUTOR

Modulatory Actions of the Glycine Receptor ß Subunit on the Positive Allosteric Modulation of Ethanol in a2 Containing Receptors

FRONTIERS IN MOLECULAR NEUROSCIENCE 2021 ARTÍCULO WOS - SCOPUS AUTOR

Presence of ethanol-sensitive and ethanol-insensitive glycine receptors in the ventral tegmental area and prefrontal cortex in mice

BRITISH JOURNAL OF PHARMACOLOGY 2021 ARTÍCULO WOS - SCOPUS AUTOR

Glycine Receptors

SIN REVISTA 2021 CAPÍTULO DE LIBRO AUTOR

Influence of nonsynaptic a1 glycine receptors on ethanol consumption and place preference

ADDICTION BIOLOGY 2020 ARTÍCULO WOS - SCOPUS AUTOR

Modulation of glycine receptor single-channel conductance by intracellular phosphorylation

SCIENTIFIC REPORTS 2020 ARTÍCULO WOS - SCOPUS AUTOR

Characterization of a new molecule capable of inhibiting several steps of the amyloid cascade in Alzheimer's disease

NEUROBIOLOGY OF DISEASE 2020 ARTÍCULO WOS - SCOPUS AUTOR

Gonadal hormone-independent sex differences in GABA(A) receptor activation in rat embryonic hypothalamic neurons

BRITISH JOURNAL OF PHARMACOLOGY 2020 ARTÍCULO WOS - SCOPUS AUTOR

Ethanol consumption and sedation are altered in mice lacking the glycine receptor alpha 2 subunit

BRITISH JOURNAL OF PHARMACOLOGY 2020 ARTÍCULO WOS - SCOPUS AUTOR

Inhibition of the Glycine Receptor alpha 3 Function by Colchicine

FRONTIERS IN PHARMACOLOGY 2020 ARTÍCULO WOS - SCOPUS AUTOR

Gabapentin Inhibits Multiple Steps in the Amyloid Beta Toxicity Cascade

ACS CHEMICAL NEUROSCIENCE 2020 ARTÍCULO WOS - SCOPUS AUTOR

Changes in neuronal excitability and synaptic transmission in nucleus accumbens in a transgenic Alzheimer's disease mouse model

SCIENTIFIC REPORTS 2020 ARTÍCULO WOS - SCOPUS AUTOR

Complex Interaction between Resident Microbiota and Misfolded Proteins: Role in Neuroinflammation and Neurodegeneration

CELLS 2020 REVIEW WOS - SCOPUS AUTOR

Reduced sedation and increased ethanol consumption in knock-in mice expressing an ethanol insensitive alpha 2 subunit of the glycine receptor

NEUROPSYCHOPHARMACOLOGY 2020 ARTÍCULO WOS - SCOPUS AUTOR

17 Oxo Sparteine and Lupanine, Obtained from Cytisus scoparius, Exert a Neuroprotection against Soluble Oligomers of Amyloid-beta Toxicity by Nicotinic Acetylcholine Receptors

JOURNAL OF ALZHEIMERS DISEASE 2019 ARTÍCULO WOS - SCOPUS COAUTOR

Inhibitory Actions of Tropeines on the alpha 3 Glycine Receptor Function

FRONTIERS IN PHARMACOLOGY 2019 ARTÍCULO WOS - SCOPUS AUTOR

Large Intracellular Domain-Dependent Effects of Positive Allosteric Modulators on Glycine Receptors

ACS CHEMICAL NEUROSCIENCE 2019 ARTÍCULO WOS - SCOPUS AUTOR

High ethanol sensitive glycine receptors regulate firing in D1 medium spiny neurons in the nucleus accumbens

NEUROPHARMACOLOGY 2019 ARTÍCULO WOS - SCOPUS AUTOR

P2X receptor overexpression induced by soluble oligomers of amyloid beta peptide potentiates synaptic failure and neuronal dyshomeostasis in cellular models of alzheimer´s disease

NEUROPHARMACOLOGY 2018 ARTÍCULO WOS - SCOPUS COAUTOR

Prevention of Synaptic Alterations and Neurotoxic Effects of PAMAM Dendrimers by Surface Functionalization

NANOMATERIALS 2018 ARTÍCULO WOS - SCOPUS COAUTOR

Presence of Inhibitory Glycinergic Transmission in Medium Spiny Neurons in the Nucleus Accumbens

FRONTIERS IN MOLECULAR NEUROSCIENCE 2018 ARTÍCULO WOS - SCOPUS AUTOR

Effect of Cholesterol on Membrane Fluidity and Association of A beta Oligomers and Subsequent Neuronal Damage: A Double-Edged Sword

FRONTIERS IN AGING NEUROSCIENCE 2018 ARTÍCULO WOS - SCOPUS COAUTOR

Association between Alzheimer's Disease and Oral and Gut Microbiota: Are Pore Forming Proteins the Missing Link?

JOURNAL OF ALZHEIMERS DISEASE 2018 REVIEW WOS - SCOPUS AUTOR

Role of membrane GM1 on early neuronal membrane actions of A beta during onset of Alzheimer's disease

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 2017 ARTÍCULO WOS - SCOPUS AUTOR

Presence of ethanol-sensitive glycine receptors in medium spiny neurons in the mouse nucleus accumbens

JOURNAL OF PHYSIOLOGY-LONDON 2017 ARTÍCULO WOS - SCOPUS AUTOR

ATP leakage induces P2XR activation and contributes to acute synaptic excitotoxiciw induced by soluble oligomers of beta-amyloid peptide in hippocampal neurons

NEUROPHARMACOLOGY 2016 ARTÍCULO WOS - SCOPUS COAUTOR

Functional modulation of glycine receptors by the alkaloid gelsemine

BRITISH JOURNAL OF PHARMACOLOGY 2016 ARTÍCULO WOS - SCOPUS COAUTOR

Reversal of Ethanol-Induced Intoxication by a Novel Modulator of Gß¿ Potentiation of Glycine Receptor

JOURNAL OF BIOLOGICAL CHEMISTRY 2016 ARTÍCULO WOS - SCOPUS COAUTOR

Structure and Pharmacologic Modulation of Inhibitory Glycine Receptors

MOLECULAR PHARMACOLOGY 2016 ARTÍCULO WOS - SCOPUS AUTOR

The Level of NMDA Receptor in the Membrane Modulates Amyloid-beta Association and Perforation

JOURNAL OF ALZHEIMERS DISEASE 2016 ARTÍCULO WOS - SCOPUS AUTOR

Potentiation of gamma aminobutyric acid receptors (GABAaR) by ethanol: how are inhibitory receptors affected?

FRONTIERS IN CELLULAR NEUROSCIENCE 2016 ARTÍCULO WOS - SCOPUS AUTOR

Differential membrane toxicity of amyloid-B fragments by pore forming mechanisms

JOURNAL OF ALZHEIMERS DISEASE 2016 ARTÍCULO WOS - SCOPUS AUTOR

Membrane Damage Induced by Amyloid Beta and a Potential Link with Neuroinflammation

CURRENT PHARMACEUTICAL DESIGN 2016 ARTÍCULO WOS - SCOPUS AUTOR

Evidence for a-helices in the large intracellular domain mediating modulation of the alpha 1 glycine receptor by ethanol and GBy

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 2015 ARTÍCULO WOS - SCOPUS AUTOR

Low concentrations of ethanol protect against synaptotoxicity induced by AB in hippocampal neurons

NEUROBIOLOGY OF AGING 2015 ARTÍCULO WOS - SCOPUS AUTOR

Neurotoxicity of AB Explained by its Association to Plasma Membranes

SIN REVISTA 2015 CAPÍTULO DE LIBRO AUTOR

ALZHEIMER'S A BETA INTERACTS WITH CELLULAR PRION PROTEIN INDUCING NEURONAL MEMBRANE DAMAGE AND SYNAPTOTOXICITY

NEUROBIOLOGY OF AGING 2015 ARTÍCULO WOS - SCOPUS AUTOR

Extracellular a-synuclein alters synaptic transmission in brain neurons by perforating the neuronal plasma membrane

JOURNAL OF NEUROCHEMISTRY 2015 ARTÍCULO WOS - SCOPUS AUTOR

Features of alpha-synuclein that could explain the progression and irreversibility of parkinson's disease

FRONTIERS IN NEUROSCIENCE 2015 ARTÍCULO WOS - SCOPUS AUTOR

Control of Ethanol sensitivity of the Glycene receptor a3 Subunit by Transmembrane 2, the Intracellular Splice Cassette and C-Terminal Domain

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 2015 ARTÍCULO WOS - SCOPUS AUTOR

Ethanol effects on glycinergic transmission: From molecular pharmacology to behavior responses

PHARMACOLOGICAL RESEARCH 2015 ARTÍCULO WOS - SCOPUS AUTOR

Modulation of Neuronal Nicotinic Receptor by Quinolizidine Alkaloids Causes Neuroprotection on a Cellular Alzheimer Model

JOURNAL OF ALZHEIMERS DISEASE 2014 ARTÍCULO WOS - SCOPUS COAUTOR

Copper-uptake is critical for the down regulation of synapsin and dynamin induced by neocuproine: modulation of synaptic activity in hippocampal neurons

FRONTIERS IN AGING NEUROSCIENCE 2014 ARTÍCULO WOS - SCOPUS AUTOR

PSD95 Suppresses Dendritic Arbor Development in Mature Hippocampal Neurons by Occluding the Clustering of NR2B-NMDA Receptors

PLOS ONE 2014 ARTÍCULO WOS - SCOPUS COAUTOR

Altered sedative effects of ethanol in mice with a1 glycine receptor subunits that are insensitive to GBy modulation

NEUROPSYCHOPHARMACOLOGY 2014 ARTÍCULO WOS - SCOPUS AUTOR

Rapamycin protects against A beta-induced synaptotoxicity by increasing presynaptic activity in hippocampal neurons

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 2014 ARTÍCULO WOS - SCOPUS AUTOR

Nature of the neurotoxic membrane actions of amyloid-beta on hippocampal neurons in Alzheimer's disease

NEUROBIOLOGY OF AGING 2014 ARTÍCULO WOS - SCOPUS AUTOR

Effects of ethanol on glycinergic synaptic currents in mouse spinal cord neurons

JOURNAL OF NEUROPHYSIOLOGY 2014 ARTÍCULO WOS - SCOPUS AUTOR

Inhibition of amyloid beta-induced synaptotoxicity by a pentapeptide derived from the glycine zipper region of the neurotoxic peptide

NEUROBIOLOGY OF AGING 2013 ARTÍCULO WOS - SCOPUS AUTOR

Synaptic Silencing and Plasma Membrane Dyshomeostasis induced by Amyloid-b peptide are Prevented by Aristotelia chilensis Enriched Extract

JOURNAL OF ALZHEIMERS DISEASE 2012 ARTÍCULO WOS - SCOPUS COAUTOR

Inhibition of the Ethanol-induced Potentiation of a1 Glycine Receptor by a Small Peptide That Interferes with Gby Binding

JOURNAL OF BIOLOGICAL CHEMISTRY 2012 ARTÍCULO WOS - SCOPUS COAUTOR

Blueberry Extracts protect Testis from Hypobaric Hypoxia Induced Oxidative Stress in Rats

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY 2012 ARTÍCULO WOS - SCOPUS AUTOR

The basic property of Lys385 is important for potentiation of the human a1 glycine receptor by ethanol

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 2012 ARTÍCULO WOS - SCOPUS AUTOR

An extracellular mechanism that can explain the neurotoxic effects of a-synuclein aggregates in the brain

FRONTIERS IN PHYSIOLOGY 2012 ARTÍCULO WOS - SCOPUS AUTOR

Inhibitory activities on Mammalian Central Nervous System Receptors and Computational Studies of Three Sesquiterpene lactones from Coraria ruscifolia subsp. Ruscifolia

CHEMICAL & PHARMACEUTICAL BULLETIN 2011 ARTÍCULO WOS - SCOPUS COAUTOR

Biphasic effects of copper on neurotransmission in rat hippocampal neurons

JOURNAL OF NEUROCHEMISTRY 2011 ARTÍCULO WOS - SCOPUS COAUTOR

Ab Oligomers Induce Glutamate Release ferom Hippocampal Neurons

CURRENT ALZHEIMER RESEARCH 2011 ARTÍCULO WOS - SCOPUS AUTOR

Allosteric modulation of retinal GABA receoptors by ascorbic acid

JOURNAL OF NEUROSCIENCE 2011 ARTÍCULO WOS - SCOPUS AUTOR

Soluble Ab(1-40) peptide increases excitatory neurotransmission and induces epileptiform activity in hippocampal neurons.

JOURNAL OF ALZHEIMERS DISEASE 2011 ARTÍCULO WOS - SCOPUS AUTOR

Activated G protein as subunits increase the ethanol sensitivity of human glycine receptors.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 2011 ARTÍCULO WOS - SCOPUS AUTOR

A single phenylalanine residue in the main intracellular loop of a1 y-aminobutyric acid type A and glycine receptors influences their sensitivity to propofol.

ANESTHESIOLOGY 2011 ARTÍCULO WOS - SCOPUS AUTOR

Synaptic failure and adenosine triphosphate imbalance induced by amyloid-B aggregates are prevented by blueberry-enriched polyphenol extract

JOURNAL OF NEUROSCIENCE RESEARCH 2011 ARTÍCULO WOS - SCOPUS COAUTOR

Canonical Wnt3a Modulates Intracellular Calcium and Enhances Excitatory Neurotransmission in Hippocampal Neurons

JOURNAL OF BIOLOGICAL CHEMISTRY 2010 ARTÍCULO WOS - SCOPUS COAUTOR

Potentiation and Inhibition of Glycine Receptors by Tutin

NEUROPHARMACOLOGY 2010 ARTÍCULO WOS - SCOPUS COAUTOR

Molecular Requirements for Ethanol Differential Allosteric Modulation of Glycine Receptors Based on Slective Gbetagamma Modulation

JOURNAL OF BIOLOGICAL CHEMISTRY 2010 ARTÍCULO WOS - SCOPUS AUTOR

Beta-amyloid causes depletion of synaptic vesicles leading to neurotransmission failure.

JOURNAL OF BIOLOGICAL CHEMISTRY 2010 ARTÍCULO WOS - SCOPUS AUTOR

Synaptotoxicity of Alzheimer Beta Amyloid Can Be Explained by Its Membrane Perforating Property

PLOS ONE 2010 ARTÍCULO WOS - SCOPUS AUTOR

Degradation of 2,4,6-tribromophenol and 2,4,6-trichlorophenol by Aerobic Heterotrophic Bacteria Present in Psychrophilic Lakes

WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY 2009 ARTÍCULO WOS - SCOPUS COAUTOR

Blockade of Ethanol-Induced Potentiation of Glycine Receptors by a Peptide that Interferes with Gbetasigma Binding

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 2009 ARTÍCULO WOS - SCOPUS COAUTOR

Alzheimer Beta-Amyloid Block Epileptiform Activity in Hippocampal Neurons

MOLECULAR AND CELLULAR NEUROSCIENCE 2009 ARTÍCULO WOS - SCOPUS AUTOR

Sustained Increase of Ca+2 Oscillations After Chronic TRPV1 Receptor Activation with Capsaicin in Cultured Spinal Neurons

BRAIN RESEARCH 2008 ARTÍCULO WOS - SCOPUS AUTOR

A Selective G Betagamma-Linked Intracellular Mechanism for Modulation of a Ligand-Gated Ion Channel by Ethanol

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2008 ARTÍCULO WOS - SCOPUS AUTOR

Inhibitory Effects of Tutin on Glycine Receptors in Spinal Neurons

EUROPEAN JOURNAL OF PHARMACOLOGY 2007 ARTÍCULO WOS - SCOPUS COAUTOR

Regulation of Glycinergic and GABAergic synaptogenesis by Brain-Derived Neurotrophic Factor in Developing Spinal Neurons

NEUROSCIENCE 2007 ARTÍCULO WOS - SCOPUS AUTOR

Anti-Homeostatic Synaptic Plasticity of Glycine Receptor Function After Chronic Strychnine in Developing Cultured Mouse Spinal Neurons

JOURNAL OF NEUROCHEMISTRY 2007 ARTÍCULO WOS - SCOPUS AUTOR

The Classic Receptor for 1 alfa,25-dihydroxy Vitamin D3 is Required for Non-Genomic Actions of 1alfa,25-dihydroxy Vitamin D3 in Osteosarcoma Cells

JOURNAL OF CELLULAR BIOCHEMISTRY 2006 ARTÍCULO WOS - SCOPUS COAUTOR

Historical and Current Perspectives of Neuroactive Compounds Derived from Latin America

JOURNAL OF MEDICINAL CHEMISTRY 2006 ARTÍCULO WOS - SCOPUS AUTOR

Molecular Determinants for G Protein beta(gamma) Modulation of Ionotropic Glycine Receptors

JOURNAL OF BIOLOGICAL CHEMISTRY 2006 ARTÍCULO WOS - SCOPUS AUTOR

The Presence of Glia Stimulates the Appearance of Glycinergic Synaptic Transmission in Spinal Cord Neurons

MOLECULAR AND CELLULAR NEUROSCIENCE 2005 ARTÍCULO WOS - SCOPUS AUTOR

Ependymal Cell Di Erentiation and GLUT1 Expression is a Synchronous Process in the Ventricular Wall

NEUROCHEMICAL RESEARCH 2005 ARTÍCULO WOS - SCOPUS COAUTOR

Sodium Vitamin C Cotransporter SVCT2 Is Expressed in Hypothalamic Glial Cells

GLIA 2005 ARTÍCULO WOS - SCOPUS COAUTOR

Glycinergic and GABAergic Synaptic Transmission are Differentially Affected by Gephyrin in Spinal Neurons

BRAIN RESEARCH 2005 ARTÍCULO WOS - SCOPUS AUTOR

Changes on the Properties of Glycine Receptors During Neuronal Development

BRAIN RESEARCH REVIEWS 2004 ARTÍCULO WOS AUTOR

S-Methylcysteine May Be a Causal Factor in Monohalomethane Neurotoxicity

NEUROTOXICOLOGY 2004 ARTÍCULO WOS - SCOPUS COAUTOR

Developmental-Dependent Action of Microtubule Depolymerization on the Function and Structure of Synaptic Glycine Receptor Clusters in Spinal Neurons

JOURNAL OF NEUROPHYSIOLOGY 2004 ARTÍCULO WOS - SCOPUS AUTOR

Modulation of Glycine-Activated Ion Channel Function by G-Protein Betagamma Subunits

NATURE NEUROSCIENCE 2003 ARTÍCULO WOS - SCOPUS AUTOR

GABAA Receptors as Molecular Sites of Ethanol Action. Direct or Indirect Actions?

CURRENT TOPICS IN MEDICINAL CHEMISTRY 2002 ARTÍCULO WOS - SCOPUS AUTOR

Effects of Chronic Ethanol Treatment on g-Aminobutyric AcidA and Glycine Receptors in Mouse Glycinergic Spinal Neurons

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 2002 ARTÍCULO WOS - SCOPUS AUTOR

High-Affinity Sodium-Vitamin C Co-Transporters (SVCT) Expression in Embryonic Mouse Neurons

JOURNAL OF NEUROCHEMISTRY 2001 ARTÍCULO WOS - SCOPUS COAUTOR